Spiders are one of the Enemies & Wild Animals of NieR Replicant. They are the Giant Spiders that roam around the Southern Plains and spew poison.
The poisonous spiders are located at the Southern Plains and linger inside Emil's Manor. They do not appear in Act II of the game.
Spiders are fairly easy enemies to defeat. They sometimes project orbs of poison, shown as the green clouds, that can only be countered with Antidotal Weed.
Poison - A status effect that damaged NieR's HP over time when left untreated
Possible item drops upon killing a Spider: